SimAnt oldie but goldie – Mac-Forums.com. Nice help from louishen:
Download SimAnt – The Electronic Ant Colony | Abandonia
I just installed this and it works great. It can be a little tricky to set up. The easiest way is to create a games folder in your user folder in the Finder and then mount it using this command in DosBox.
mount c: ~/games
Now off to trying SimAnt!